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Korean Cancer Study Group 
Webzine Vol.38  DEC 2025 
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논문 발간현황 2024.11 - 2025.07

▶ LU21-01 | PMID : 41202701

Phase II study of lazertinib and pemetrexed in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer with leptomeningeal metastases: the KCSG LU 21-01, LAZARUS study

Lung Cancer. 2025 Nov 1:210:108809.



▶ HN15-16 | PMID : 40967067

Identifying predictive markers of head and neck squamous cell carcinoma in an umbrella trial (KCSG HN 15-16 TRIUMPH trial)

ESMO Open. 2025 Oct;10(10):105772.



▶ GU22-13 | PMID : 41084176

Real World Efficacy of 1st-Line Nivolumab Plus Ipilimumab and its Practical Predictive Biomarkers in Advanced Renal Cell Carcinoma: First Analysis from RENOIR Study (KCSG GU22-13)

Cancer Res Treat. 2025 Oct 13.



▶ HB19-14 | PMID : 41037761

Artificial Intelligence-Powered Human Epidermal Growth Factor Receptor 2 Quantification and Clinical Outcomes in Human Epidermal Growth Factor Receptor 2-Positive Biliary Tract Cancer Treated With Trastuzumab Plus Folinic Acid, Fluorouracil, and Oxaliplatin.

JCO Precis Oncol. 2025 Oct:9:e2500510.



▶ HB23-04 | PMID : 41038766

Multicenter phase II trial of lenvatinib in patients with advanced hepatocellular carcinoma after progression on first-line atezolizumab plus bevacizumab

J Hepatol. 2025 Sep 4:S0168-8278(25)02457-2.



▶ HPM25-17 | PMID : 40635454

Barriers to Clinical Trial Enrollment: KCSG Survey-Based Perspectives of Medical Oncologists, Patients, and Their Caregivers

Cancer Res Treat. 2025 Jul 7.



▶ HN15-16 | PMID : 39727015

Clinical Impact of TP53 Mutations in Patients with Head and Neck Cancer Who Were Treated with Targeted Therapies or Immunotherapy

Cancer Res Treat. 2025 Jul;57(3):709-719.



▶ CO22-12 | PMID : 40855542

Platform study of circulating tumor DNA directed adjuvant chemotherapy in colon cancer (CLAUDIA colon cancer, KCSG CO22-12)

BMC Cancer. 2025 Aug 25;25(1):1373.



▶ BR19-10 | PMID : 40688164

Prevalence of germline BRCA1/2 pathogenic variants in unselected Korean patients with HER2-negative metastatic breast cancer: a nationwide prospective study (KCSG BR19-10)

Lancet Reg Health West Pac. 2025 Jul 5:60:101622.



▶ BR18-21 | PMID : 40783751

Randomized, phase II trial to evaluate the efficacy and safety of atezolizumab plus capecitabine adjuvant therapy compared to capecitabine monotherapy for triple receptor-negative breast cancer with residual invasive cancer after neoadjuvant chemotherapy (MIRINAE trial, KCSG-BR18-21)

BMC Cancer. 2025 Aug 25;25(1):1373.



▶ ST18-03 | PMID : 40399487

Multicenter phase Ib/II study of second-line durvalumab and tremelimumab in combination with paclitaxel in patients with biomarker-selected metastatic gastric cancer

Br J Cancer. 2025 May 21.



▶ HN18-07 | PMID : 39701091

Phase II Trial of Neoadjuvant Docetaxel/Cisplatin/5-Fluorouracil Combined with Pegteograstim for Unresectable, Locally Advanced Sinonasal Squamous Cell Carcinoma: KCSG HN18-07

Cancer Res Treat. 2024 Dec 16.



▶ BR21-15 | PMID : 40383091

Nationwide real-world practice pattern and clinical data of palbociclib in HR (+), HER2 (-) metastatic breast cancer patients in Korea (KCSG BR21-15)

Breast. 2025 May 12:82:104500.



▶ AL20-17 | PMID : 40211931

Phase II study evaluating the safety and efficacy of neratinib and trastuzumab biosimilar in patients with HER2 mutated advanced solid tumors: KCSG AL20-17/KM23 trial

Cancer Commun (Lond). 2025 Apr 11.


▶ LU23-15 | PMID : 39901702

Delayed central nervous system progression with atezolizumab plus chemotherapy in extensive-stage small-cell lung cancer (LU23-15)

Lung Cancer. 2025 Mar:201:108455.



▶ HN15-16 | PMID : 39901702

Differential Efficacy of Alpelisib by PIK3CA Mutation Site in Head and Neck Squamous Cell Carcinoma: An Analysis from the KCSG HN 15-16 TRIUMPH Trial

Cancer Res Treat. 2025 Jan 31.



▶ GU20-03 | PMID : 39961593

A Multicenter Phase II Study of Modified FOLFIRINOX for First-line Treatment for Advanced Urachal Cancer (ULTMA; KCSG GU20-03)

Cancer Res Treat. 2025 Feb 13.



▶ BR15-10 | PMID : 39978378

Palbociclib plus endocrine therapy versus capecitabine in premenopausal women with hormone receptor-positive, HER2-negative metastatic breast cancer (Young-PEARL): overall survival analysis of a randomised, open-label, phase 2 study

Lancet Oncol. 2025 Mar;26(3):343-354.



▶ GU16-05 | PMID : 39727010

Pemetrexed Maintenance versus Observation in Patients with Advanced Urothelial Carcinoma Who Completed First-line Platinum-based Chemotherapy without Disease Progression (PREMIER, KCSG GU16-05)

Cancer Res Treat. 2024 Dec 27.



▶ AL20-05 | PMID : 39305545

Nationwide precision oncology pilot study: KOrean Precision Medicine Networking Group Study of MOlecular profiling-guided therapy based on genomic alterations in advanced solid tumors (KOSMOS) KCSG AL-20-05

ESMO Open. 2024 Oct;9(10):103709.



▶ BR17-06 | PMID : 39174547

A phase 3 study (PATHWAY) of palbociclib plus tamoxifen in patients with HR-positive/HER2-negative advanced breast cancer

NPJ Breast Cancer. 2024 Aug 22;10(1):76.



▶ HB22-21 | PMID : 40255875

Real-World Study of Systemic Treatment after First-Line Atezolizumab plus Bevacizumab for Hepatocellular Carcinoma in Asia-Pacific Countries

Liver Cancer. 2024 Aug 20;14(2):127-141



▶ PC20-12 | PMID : 39028339

Efficacy of transdermal buprenorphine patch for managing withdrawal symptoms in patients with cancer physically dependent on prescription opioids

The Oncologist. 2024 29, e1593-1603



▶ LU22-18 | PMID : 39619275

Clinical Outcomes of Maintenance Durvalumab After Definitive Concurrent Chemoradiotherapy in Unresectable Locally Advanced Stage III NSCLC According to EGFR and ALK Status: Korean Cancer Study Group LU-22-18

JTO Clin Res Rep. 2024 Oct 16;5(12):100734.



▶ UN18-06 | PMID : 39422602

Phase 2 trial of avelumab in combination with gemcitabine in advanced leiomyosarcoma as a second-line treatment (EAGLES, Korean Cancer Study Group UN18-06)

Cancer. 2024 Oct 18.



▶ BR18-16 | PMID : 39105849

Genomic and transcriptomic profiles associated with response to eribulin and nivolumab combination in HER-2-negative metastatic breast cancer

Cancer Immunol Immunother. 2024 Aug 6;73(10):197.



▶ GU23-08 | PMID : 39312854

Four versus six cycles of platinum-based chemotherapy for advanced Urothelial carcinoma in the era of immune checkpoint inhibitors: A retrospective cohort study (FOCUS, KCSG-GU23-08)

Curr Probl Cancer. 2024 Sep 22:53:101149. Online ahead of print.



▶ AL19-17 | PMID : 39214049

A phase II study of tepotinib in patients with advanced solid cancers harboring MET exon 14 skipping mutations or amplification (KCSG AL19-17)

ESMO Open. 2024 Sep;9(9):103668.



▶ LU20-15 | PMID : 39145962

Lazertinib in EGFR-Variant Non-Small Cell Lung Cancer With CNS Failure to Prior EGFR Tyrosine Kinase Inhibitors: A Nonrandomized Controlled Trial

JAMA Oncol. 2024 Aug 15:e242640.



▶ LU17-19 | PMID : 38986212

A phase II study of osimertinib in patients with NSCLC harboring EGFR exon 20 insertion: A multicenter trial of the Korean Cancer Study Group

Lung Cancer. 2024 Aug:194:107870.



▶ BR19-15 | PMID : 38288157

A nationwide real-world study for evaluation of effectiveness and safety of T-DM1 in patients with HER2-positive metastatic breast cancer in Korea (KCSG BR19-15)

Ther Adv Med Oncol 2024, Vol. 16: 1–15



▶ HN18-17 | PMID : 38919826

A phase 2 study of spartalizumab (PDR001) among patients with recurrent or metastatic esophageal squamous cell carcinoma (KCSG HN18-17, K-MASTER project 12)

Oncoimmunology. 2024 Jun 24;13(1):2371563.

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